Fragment (HGH Fragment 176-191) 10mg

The HGH Fragment is a modified form of amino acids 176-191 of the human Growth Hormone (GH) polypeptide. This peptide, as the name implies, is a piece of the 191 amino chain thatmakes up growth hormone, from positions 176 through 191 to be exact. This fragment has been shown to induce lipolysis, or fat breakdown, and even inhibits lipogenesis, which is thetransformation of food materials into fat stored in the body. Research studies have shown that these happens both to humans and to animals. This short aminoacid chain that make upFragment 176 is only about 10% of the length of the entire strand of growth hormone and seems to have no other typical positive or negative effects that growth hormone does such asactual growth of tissues or insulin resistance. HGH Fragment (176-191) is a sterile, non-pyrogenic, white lyophilized powder intended for subcutaneous or intramuscular injection, afterreconstitution with sterile Water for Injection (0,3% m-Cresol).

Mechanism of Action
This region consists of amino acids 176-191, and is less than 10% of the total size of the GH molecule and appears to have no effect on growth or insulin resistance. It works by mimickingthe way natural GH regulates fat metabolism but without the adverse effects on blood sugar or growth that is seen with unmodified GH.More specifically, GH cannot be used as an anti-obesity treatment due to adverse effects:
• Fluid retention
• Diabetogenic (in high doses)

On the contrary, HGH fragment can produce an inhibition of LPL activity in adipose tissue and stimulate lipolysis in adipocytes. At the same time, HGH fragment appears to have no effecton growth or insulin resistance. In that way treatment with HGH fragment cannot cause diabetogenic problems or influence the insulin metabolism. Also HGH fragment cannot cause fluidretention.

These segments of the synthetic peptide HGH Fragment (176-191) have been investigated for their in vivo effects in laboratory mice muscles. Research results have shown that HGHFrag (176-191) nave resulted to a short-period increase in blood glucose and amore sustained increase in plasma insulin, together with other fragments such as 172-191, 177-191 and178-191. In addition, the researchers have suggested that functionality of the peptide depends not only in the informational sequence but should also have the correct physicalconfiguration. Also, this fragment, being a region of high accessibility to proteases and also rich in praline, have been demonstrated to affect the conformational change in the cytoplasmicdomain of the band 3 of erythrocyte membrane protein by serving as the hinge for the pivoting of the two subdomains. This then suggest that such residue is significant in conformationalchanges be serving as sites for peripheral protein binding in some body cells.

In another study on animal subjects, they found out that a 0.5mg dosage of the said hormone increased the lipolytic activity in adipose tissues without having negative influence in theblood glucose level. Furthermore, though it behaves like a human growth hormone (HGH), it does not causes hyperglycemia because it does not compete with HGH receptors. Becauseof such effects, researchers have suggested that it might be used for the elimination of excess abdominal fat which is less significant aspect of HIV-associated lipodystrophy.Other studies claimed that protein peptide HGH fragment (176-191) actually acts or the reduction of excessive adipose tissues (body fat) such as those in the abdominal area andincreases muscle mass while enhancing the lipid content of the body In laboratory tests on fat cells from humans, HGH fragment released fat specifically from obese fat cells but not fromlean ones, reduced new fat accumulation in all fat cells and enhanced the burning of fat. HGH fragment reduces body fat in obese subjects and enhanced fat burning without changingfood consumption or inducing growth (as it does not increase IGF levels) or any other unwanted GH effect. HGH fragment has no ability to restore the body as HGH, and do not enhancesathletic performance. Its entire effectiveness is consist in the extreme mobilization of fat burning.

So as a conclusion, HGH fragment
• Reduces the most stubborn abdominal fat,
• Improves lipid profiles and lipolytic activity,
• Does not negatively impact blood glucose levels,
• Cell proliferation doesn’t occur,
• Is an extremely potent and effective fat burner.

Side effects – immediately after injection can be felt general weakness and loss of tone.

Pharmacodynamics
Since only the active fragment of HGH is used, there haven’t been observed any of the adverse reactions connected with that hormone.
Dosage
Recommended dosage of HGH Fragment (176-191):
• 0.5 mg once per day
For optimum results, a HGH fragment cycle, can be completed with Clenbuterol.
Clenbuterol is a powerful fat burner working on stimulating Beta 2 receptors which helps you to release and then burn stored fat So it can be co-operate perfectly with HGH Fragment

Notice that Clenbuterol should be ran day on -day off.

Note: Although listed options for the intake, each case must be examined individually and to consider personal and training characteristics of each person as well as possible interactions if you take other medicines. The most appropriate time of admission is directly, before bedtime.

For the administration with Balco pen – 0.1mg HGH Fragment corresponds to 2.4 divisions of the rotating scale (7).

Storage
Shelf life
• This product can be used not more than 3 years from the production date ( see box)
• After reconstitution, may be stored for a maximum of 30 days in a refrigerator at 2°C – 8°C.
• Store vials in an upright position.
• Store in a refrigerator (2°C – 8°C). Keep in the outer carton in order to protect from light.
• For one month can be stored at room temperature.