GHRP-6 (Growth Hormone Releasing Peptide – 6) is a hexapeptide with a chain comprised of 6 amino acids. It is one of several synthetic met-enkephalin analogs that include unnatural D-amino acids that were developed for their growth hormone releasing activity and are called growth hormone secretagogues. GHRP-6 is a true HGH secretagogue. This growth hormone releasing peptide is distinct from GHRH and do not act at the GHRH receptor, but instead acts at the growth hormone secretagogue receptor, now renamed as the ghrelin receptor. GHRP-6 is a sterile, non-pyrogenic, white lyophilized powder intended for subcutaneous or intramuscular injection, after reconstitution with sterile Water for Injection. Formula

Mechanism of Action
GHRP-6 is not an active fragment of growth hormone releasing hormone (GHRH). Which means it stimulates the body’s own secretion of HGH. Human Growth hormone has been shown in studies to promote lean body mass and reduce adiposity (fat). This growth hormone releasing peptide is distinct from GHRH and do not act at the GHRH receptor, but instead acts at the growth hormone secretagogue receptor, now renamed as the gh-relin receptor.

GHRP-6’s special sequence is considered to provide a signal to the body to begin secreting Growth Hormone(GH) release while also blocking Somatostatin, a hormone that inhibits Growth Hormone release. Research studies have shown that GHRP-6 stimulation of Growth Hormone has host of beneficial effects such as decreased body fat, increased muscle, and increased strength and stamina so maximizing the production and secretion can be a great addition to improved animal physical shape. Increased amounts of Growth Hormone then can cause the liver to secrete the hormone IGF-1 which has also been implicated in improving the animal body’s ability to burn fat and build muscle. Clinical cases have shown that the use of GHRP-6 was associated with increased muscle mass and a reduction of body fat. GHRP-6 has been one of the most thoroughly studied and is believed to be acting naturally on both pituitary and hypothalamic sites (Fairhall et al. 1995). This has been demonstrated in the primary pituitary cells of rats in a time-dependent and dose-dependent manner. In another study of Fairhall et al. (1995), they concluded that the major target of the GHRP-6 in vivo is the hypothalamus after observing that the GH( Growth Hormone) release induced by the central GHRP-6 administration in guinea pigs was inhibited by the central action of somatostatin. Furthermore, an inhibition by somatostatin with the activated GRF neurons ( GRF=Growth Hormone Releasing Factor), induced by GHRP-6, was observed via receptors known to be located on or near the GRF themselves. However, it was also observed that GHRP-6 had no effect on the intracellular cAMP levels unlike that of GHRP-2. This particular experiment further indicated that GHRP-6 is effectively stimulating GH release from somatotrophs through different receptors, the mechanisms of which are not yet known (Chan et al. 1989).

However, some researchers suggest that action and efficiency of growth hormone is dependent on the physical condition of the experimental unit. In humans for example, GH secretion decreases with obesity. This is contrary in the case of the GHRP-6 which showed increased (almost twice that of GHRP) GH responses when administered in obese patients (Cordido et al. 1993). Though obesity has shown affecting the efficiency of the hormone, it was also suggested that GHRP-6’s effects, at least at the dose-dependent manners, were found to be sex- and age-independent without being affected by the noadregenic pathways using the a2 adrenergic receptors (Penalva et al. 2008).

GHRP-6 Peptide is generally very well tolerated by most individuals when used at the recommended dosages of up to 0.20mg per injection. Water Retention: Caused by an increase in aldosterone, cortisol and prolactin. It is more of a problem with GHRP-2 than GHRP-6 . It will usually subside within a few weeks and can be controlled by watching your sodium (salt) intake. Tiredness: Is usually only noticed for the first few weeks as the body adjusts and can be reduced by taking injections only at night time. Increased Hunger: Often noticed with the usage of GHRP-6. Should settle after the first few weeks.
Instructions for reconstitution
Recommended dosage of GHRP-6 :
• 0.10mg once per day for anti-aging.
• Between 0.40-0.60mg, divided in two or three doses per day for muscle gain and fat loss, directed via subcutaneous injections. Optimal times for injection are: first thing in the morning, pre or post workout and at night before bed.

*After preparing the solution, mark the expiry date on the vial – up to 30 days after reconstitution of the product.

Note: Although listed options for the intake, each case must be examined individually and to consider personal and training characteristics of each person as well as possible interactions if you take other medicines.

Doping test
Athletes which are subject to doping tests and they use GHRP-6 should know that is included in the list of banned substances of WADA. The products of BALCO don’t have marking agents and this preparation can’t be detected by regular testing of the urine. In blood test its presence is also absolutely undetectable 12 hours after the intake. In sudden blood test GHRP-6 can be detected for about 6 hours after taking the preparation. Unlike direct intake of HGH the rise of levels here is close to physiological and it’s not detectable in doping test.
Shelf life
• This product can be used not more than 3 years from the production date (see box)
• After reconstitution, may be stored for a maximum of 30 days in a refrigerator at 2°C – 8°C.
• Store vials in an upright position.
• Store in a refrigerator (2°C – 8°C). Keep in the outer carton in order to protect from light.
• For one month can be stored at room temperature.
Authenticity verification
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