GHRP-2 (growth hormone-releasing peptide 2) 10mg
Growth Hormone Releasing Peptide-2 is a single, non-glycosylated oligopeptide chain containing 6 amino acids. GH-releasing peptides (GHRPs) are synthetic peptides that like GHRH act directly on pituitary somatotrophs to stimulate GH release. GHRP-2, an investigational drug, is one of the most potent members of the GHRP family. GHRP-2 is a sterile, non-pyrogenic, white lyophilized powder intended for subcutaneous or intramuscular injection, after reconstitution with sterile Water for Injection. Its chemical structure is:
GHRP-2 and GRF Analogue Interactions
It is important to know that GHRP-2 does not relate to any Growth Hormone Releasing Hormones (GHRH) peptides such as Sermorelin and CJC-1295 because it acts on differentreceptors. However, greater results occurred when administered in conjunction with a Growth Hormone Releasing Hormone (GHRH) such as CJC- 1295 (with DAC). Naturally, theseGHRP-2 peptide receptors interact with a hormone called ghrelin. Growth hormone releasing peptide -2 is a commercially synthesized, non-natural super-analog of GHRP-6 which iscapable of potent stimulatory effect on growth hormone (GH) secretion with slight stimulator effect in PRL, ACTH and levels of cortisol (Arvat et al. 1997). It is also a synthetic agonist ofghrelin that is binding with the growth hormone (GH) secretagogue receptor. GHRP-2 has been shown to affect and induce growth hormone secretion. The response of natural physiologicsystem includes increase in levels of calcium ion influx along side with increased release of growth hormones in response to this peptide.
Comparing GHRP-2 and GHRP-6
GHRP-2 is a 2nd generation GHRP just behind GHRP-6. Compared to GHRP-6, GHRP-2 is considered to be much more superior in terms of growth hormone stimulation because overlonger periods of time it maintains maximum elevations in Growth Hormone. GHRP-2 has shown to increase IGF-1 levels (Insulinlike Growth Factor 1), and even greater results happenwhen used with Growth Hormone Releasing Hormone (GHRH). It has a short half-life with peak concentrations occur ring around 15 minutes but not longer than 60 minutes. The responseof natural physiologic system includes increase in levels of calcium ion influx alongside with increased release of growth hormones in response to the high-amplitude pulsation from theGHRP-2. GHRP-2 and other ghrelin analogues increase the number of somatotropes involved in the GH pulse by inhibiting somatostatin. GHRH increases the pulse amplitude perpituitary cell or somatotrope by other means. Unlike ghrelin, GHRP-2 is not lipogenic which means that it does not induce fat storage.
Although ghrelin plays a large role in hunger, GHRP-2 as an analog of ghrelin does not increase appetite significantly.
The hunger side effects tied to GHRP-2 should be duly noted Usage of this pep tide can also come with elevated levels of cortisol and prolactin, especially if users are dosing in the higherranges – over 200mcg/injection. Another common side effect is the feeling of lethargy and tiredness upon first using GHRP-2. Water retention, tingling, numbness and decreased insulinsensitivity have also been cataloged as effects of GHRP-2. The most common positive side effect that bodybuilders and athletes will find with GHRP-2 are. decreased body fat, increaselean body mass, improved sleep, increase in IGF-1 production, increase in bone density and increase in cellular repair. WhileGHRP-2 has good and bad side effects, its would also betaken in to consideration that compared to GHRP-6,GHRP-2 is actually the mildest GHRP next in line to Ipamorelin.
Note: Although listed options for the intake, each case must be examined individually and to consider personal and training characteristics of each person as well as possible interactionsif you take other medicines.
• This product can be used not more than 3 years from the production date ( see box)
• After reconstitution, may be stored for a maximum of 30 days in a refrigerator at 2°C – 8°C.
• Store vials in an upright position.
• Store in a refrigerator (2°C – 8°C). Keep in the outer carton in order to protect from light.
• For one month can be stored at room temperature.